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  <xs:element id="stm_DeviceManufacturingChinaMember" abstract="true" name="DeviceManufacturingChinaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_NumberOfInternalTargetsWeightingOneThird" abstract="false" name="NumberOfInternalTargetsWeightingOneThird" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
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  <xs:element id="stm_NumberOfCustomerAccountedMoreThanTenPercentAccountsReceivable" abstract="false" name="NumberOfCustomerAccountedMoreThanTenPercentAccountsReceivable" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="stm_UnrecognizedTaxBenefitsAgainstExistingNetOperatingLosses" abstract="false" name="UnrecognizedTaxBenefitsAgainstExistingNetOperatingLosses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_LesseeOperatingAndFinanceLeaseLiabilityPaymentsDueYearTwo" abstract="false" name="LesseeOperatingAndFinanceLeaseLiabilityPaymentsDueYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_ProceedsFromCapitalGrantsAndOtherContributions" abstract="false" name="ProceedsFromCapitalGrantsAndOtherContributions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_TwentyFourDecemberTwoThousandTwentyMember" abstract="true" name="TwentyFourDecemberTwoThousandTwentyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_EmployeesMember" abstract="true" name="EmployeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearTwo" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_TaxesAndOtherGovernmentReceivablesNonCurrent" abstract="false" name="TaxesAndOtherGovernmentReceivablesNonCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DividendDistributionFirstInstallmentMember" abstract="true" name="DividendDistributionFirstInstallmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_GainLossOnFinancialInstrumentsNet" abstract="false" name="GainLossOnFinancialInstrumentsNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_StockBasedCompensationExcludingPayrollTaxAndSocialContributionCapitalizedAsPartOfInventory" abstract="false" name="StockBasedCompensationExcludingPayrollTaxAndSocialContributionCapitalizedAsPartOfInventory" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_NewFacilityAgreementWithCDPOneMember" abstract="true" name="NewFacilityAgreementWithCDPOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_EmployeePlanTwoThousandNineMember" abstract="true" name="EmployeePlanTwoThousandNineMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_OperatingAndFinanceLeaseLiability" abstract="false" name="OperatingAndFinanceLeaseLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_LoansAndDepositsCurrent" abstract="false" name="LoansAndDepositsCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_NewFacilityAgreementWithCDPTwoMember" abstract="true" name="NewFacilityAgreementWithCDPTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_TwentyEightJulyTwoThousandTwentyOneMember" abstract="true" name="TwentyEightJulyTwoThousandTwentyOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_DefinedContributionPlanAccruedBenefits" abstract="false" name="DefinedContributionPlanAccruedBenefits" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_LesseeOperatingAndFinanceLeaseLiabilityMaturityTableTextBlock" abstract="false" name="LesseeOperatingAndFinanceLeaseLiabilityMaturityTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_SummaryOfAccountingPoliciesLineItems" abstract="true" name="SummaryOfAccountingPoliciesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="stm_AuthorizedShareCapital" abstract="false" name="AuthorizedShareCapital" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_ClassificationOfPrePayrollTaxAndSocialContributionStockBasedCompensationExpenseIncludedInConsolidatedStatementsOfIncomeTableTextBlock" abstract="false" name="ClassificationOfPrePayrollTaxAndSocialContributionStockBasedCompensationExpenseIncludedInConsolidatedStatementsOfIncomeTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_DefinedBenefitPlans" abstract="false" name="DefinedBenefitPlans" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_LongTermDebtDenominatedByCurrenciesTableTextBlock" abstract="false" name="LongTermDebtDenominatedByCurrenciesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_ScheduleOfAllocationOfPensionPlanAssetsIncludingFairValueMeasurementsTableTextBlock" abstract="false" name="ScheduleOfAllocationOfPensionPlanAssetsIncludingFairValueMeasurementsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_SeniorUnsecuredConvertibleBondsMember" abstract="true" name="SeniorUnsecuredConvertibleBondsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_ScheduleOfMethodologiesUsedToEstimateFairValueTaleTextBlock" abstract="false" name="ScheduleOfMethodologiesUsedToEstimateFairValueTaleTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_ShortTermDeposits" abstract="false" name="ShortTermDeposits" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_LesseeOperatingAndFinanceLeaseLiabilityPaymentsDueYearFour" abstract="false" name="LesseeOperatingAndFinanceLeaseLiabilityPaymentsDueYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_PeriodOfAccumulatedOtherComprehensiveIncomeLoss" abstract="false" name="PeriodOfAccumulatedOtherComprehensiveIncomeLoss" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="stm_AdvanceFromGovernmentGrants" abstract="false" name="AdvanceFromGovernmentGrants" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_EmployeePlanTwoThousandTwentyTwoMember" abstract="true" name="EmployeePlanTwoThousandTwentyTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_LesseeOperatingAndFinanceLeaseLiabilityPaymentsDueYearThree" abstract="false" name="LesseeOperatingAndFinanceLeaseLiabilityPaymentsDueYearThree" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_SupervisoryBoardTwoThousandTwelveMember" abstract="true" name="SupervisoryBoardTwoThousandTwelveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_OperatingAndFinanceLeaseRightOfUseAsset" abstract="false" name="OperatingAndFinanceLeaseRightOfUseAsset" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_ZeroCouponDueTwoThousandAndTwentySevenTrancheBMember" abstract="true" name="ZeroCouponDueTwoThousandAndTwentySevenTrancheBMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearOne" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearOne" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_CurrencyCollarsMember" abstract="true" name="CurrencyCollarsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_ScheduleOfRightOfUseAssetsObtainedInExchangeForOperatingLeaseAndFinanceLiabilitiesTableTextBlock" abstract="false" name="ScheduleOfRightOfUseAssetsObtainedInExchangeForOperatingLeaseAndFinanceLiabilitiesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_ComputerAndResearchAndDevelopmentEquipmentMember" abstract="true" name="ComputerAndResearchAndDevelopmentEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_FoundryPurchaseMember" abstract="true" name="FoundryPurchaseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationThereafter" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationThereafter" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredIncomeTaxExpenseBenefitRelatingToUnvestedShareBasedCompensationExpense" abstract="false" name="DeferredIncomeTaxExpenseBenefitRelatingToUnvestedShareBasedCompensationExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DefferredTaxAssetsOperatingLossCarryforwardsTaxCreditsAndOtherTaxAttributes" abstract="false" name="DefferredTaxAssetsOperatingLossCarryforwardsTaxCreditsAndOtherTaxAttributes" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_FundingProgramLoansDueTwoThousandAndThirtyOneFloatingInterestRateAtEuriborOneMember" abstract="true" name="FundingProgramLoansDueTwoThousandAndThirtyOneFloatingInterestRateAtEuriborOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_DebtInstrumentConvertibleConversionPremiumPercentage" abstract="false" name="DebtInstrumentConvertibleConversionPremiumPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="stm_WaferFabCrollesFranceMember" abstract="true" name="WaferFabCrollesFranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_A2030Member" abstract="true" name="A2030Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_DeferredTaxAssetExpirationYearDomain" abstract="true" name="DeferredTaxAssetExpirationYearDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_TwentySevenJulyTwoThousandTwentyTwoMember" abstract="true" name="TwentySevenJulyTwoThousandTwentyTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesWaived" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesWaived" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="stm_MoreThan12MonthsAbstract" abstract="true" name="MoreThan12MonthsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="stm_ExecutiveCommitteeMember" abstract="true" name="ExecutiveCommitteeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_BusinessCombinationsAndGoodwillPolicyPolicyTextBlock" abstract="false" name="BusinessCombinationsAndGoodwillPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="stm_OtherForeignCountryMember" abstract="true" name="OtherForeignCountryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_LesseeOperatingAndFinanceLeaseLiabilityPaymentsDue" abstract="false" name="LesseeOperatingAndFinanceLeaseLiabilityPaymentsDue" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DividendDistributionThirdInstallmentMember" abstract="true" name="DividendDistributionThirdInstallmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_SeventeenJuneTwoThousandTwentyMember" abstract="true" name="SeventeenJuneTwoThousandTwentyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="stm_LesseeOperatingAndFinanceLeasesTextBlock" abstract="false" name="LesseeOperatingAndFinanceLeasesTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
</xs:schema>
